This new Restylane filler features their proprietary XpresHAn technology, an enhanced hyaluronic acid that provides smooth, flexible, natural-looking results with increased flexibility. Restylane Refyne is thicker than its counterpart Restylane Defyne, which is formulated to fill in mild-to-moderate nasolabial folds and marionette lines. This filler provides long-lasting, natural-looking results. It smooths nasolabial folds, the lines that run from the nose to the corners of the mouth. It also fills marionette lines, the creases that run from the corners of the mouth to the chin. It also gives reliable support that is subtle and flexible.